Manuscript Number : IJSRST196653

Review on Hot Melt Extrusion Technology and it's Application

Authors(5) :-Mali A. S., Gavali K. V., Choudhari R. G., Anekar V. P., Gavhane Y. N.

The use of hot-melt extrusion (HME) within the pharmaceutical industry is steadily increasing, due to proven its ability to efficiently manufacture novel products. With the use of HME we can increase solubility and bioavailability of the API. HME has proven to be a robust method of producing numerous drug delivery systems like modified, controlled and targeted drug delivery systems. resulting improved bioavailability as well as taste masking of bitter active pharmaceutical ingredients (APIs). Hot-melt extrusion techniques are pragmatic in the manufacture of a variety of dosage forms and formulations such as granules, pellets, tablets, suppositories, implants, stents, transdermal systems and ophthalmic inserts. In This paper we review about the types of Extruder, solid dispersion and Application of the HME to the pharmaceutical industries.

Authors and Affiliations

Mali A. S.
Department of Pharmaceutics, Government College of Pharmacy Karad, Tal - Karad , Dist - Satara, Maharashtra, India
Gavali K. V.
Department of Pharmaceutics, Government College of Pharmacy Karad, Tal - Karad , Dist - Satara, Maharashtra, India
Choudhari R. G.
Department of Pharmaceutics, Government College of Pharmacy Karad, Tal - Karad , Dist - Satara, Maharashtra, India
Anekar V. P.
Department of Pharmaceutics, Government College of Pharmacy Karad, Tal - Karad , Dist - Satara, Maharashtra, India
Gavhane Y. N.
Department of Pharmaceutics, Government College of Pharmacy Karad, Tal - Karad , Dist - Satara, Maharashtra, India

Hot-Melt Extrusion , Targeted Drug Delivery, Bioavailability.

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Publication Details

Published in : Volume 6 | Issue 6 | November-December 2019
Date of Publication : 2019-12-30
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 253-260
Manuscript Number : IJSRST196653
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Mali A. S., Gavali K. V., Choudhari R. G., Anekar V. P., Gavhane Y. N., " Review on Hot Melt Extrusion Technology and it's Application", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 6, Issue 6, pp.253-260, November-December-2019. Available at doi : https://doi.org/10.32628/IJSRST196653    
Journal URL : https://ijsrst.com/IJSRST196653
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